Other Graham Lab Members
The focus of the Graham group is diverse, encompassing all aspects of chemokine biology from the way they signal to their multiple roles in healthy and diseased tissues in the body.
Dr. Elaine Leung
Elaine is a Wellcome Trust Clinical Research Training Fellow in women’s health at the University of Glasgow. Her PhD investigates the role of Natural Killer cells in oncolytic (anti-cancer) viral therapy in ovarian cancer. In addition, her project evaluates the changes in chemokines and cytokines of malignant cells infected with oncolytic adenoviruses and they may influence efficacy of this new class of cancer therapy. Because adenovirus replication is species-specific, her work involves functional immune assays using sorted human immune cells from primary tumour samples from women with ovarian cancer.
Dr. Yaser Al-Madhagi
I am a visiting fellow, a CRG member working under the supervision of Gerry Graham. I joined the group in September 2019. My research focus is on the role of chemokine receptors in the metastasis of cancer. I use in vivo models of cancer to investigate this, as well as various techniques like Cell Culture, Histochemistry and Flow Cytometry.
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Dr. Hanna Johnsson
"As a Rheumatology trainee I have become interested in why some patients with psoriasis develop psoriatic arthritis, which is distinct from rheumatoid arthritis. ACKR2 limits inflammation in psoriasis, and my project 'ACKR2 and the restriction of inflammatory spread in arthropathies' aims to determine if ACKR2 also limits inflammation in psoriatic arthritis, and plays a role in determining the tissue specificity of psoriatic and rheumatoid arthritis".
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I am a Medical Research Council funded Clinical Research Training Fellow. Immune cells are essential to maintaining oral health, but they also play an important role in many oral immune mediated diseases; such as gum diseases. However, we have a limited understanding of how immune cells travel specifically to the mouth in health or disease. My PhD focuses on identifying molecules that regulate immune cell trafficking to oral mucosa in health and identifying if these molecules change during non-specific inflammation and antigen specific immune responses. By understanding how immune cells move to the mouth in health we can better identify if specific molecules are involved different inflammatory diseases that affect the mouth. This in turn may help identify new therapeutic targets for the treatment of multiple debilitating immune mediated oral conditions.
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