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2009

Liver X receptor agonism promotes articular inflammation in murine collagen-induced arthritis. Asquith DL, Miller AM, Hueber AJ, McKinnon HJ, Sattar N, Graham GJ, McInnes IB. Arthritis and Rheumatism

 

Structure-function dissection of D6, an atypical scavenger receptor. Nibbs RJ, McLean P, McCulloch C, Riboldi-Tunnicliffe A, Blair E, Zhu Y, Isaacs N, Graham GJ. Methods in Enzymology

 

A TLR2 ligand suppresses inflammation by modulation of chemokine receptors and redirection of leukocyte migration. McKimmie CS, Moore M, Fraser AR, Jamieson T, Xu D, Burt C, Pitman NI, Nibbs RJ, McInnes IB, Liew FY, Graham GJ. Blood

 

D6 and the atypical chemokine receptor family: novel regulators of immune and inflammatory processes. Graham GJ. European Journal of Immunology

 

The Duffy antigen receptor for chemokines transports chemokines and supports their promigratory activity. Pruenster M, Mudde L, Bombosi P, Dimitrova S, Zsak M, Middleton J, Richmond A, Graham GJ, Segerer S, Nibbs RJ, Rot A. Nature Immunology

2008

Hemopoietic cell expression of the chemokine decoy receptor D6 is dynamic and regulated by GATA1. McKimmie CS, Fraser AR, Hansell C, Gutiérrez L, Philipsen S, Connell L, Rot A, Kurowska-Stolarska M, Carreno P, Pruenster M, Chu CC, Lombardi G, Halsey C, McInnes IB, Liew FY, Nibbs RJ, Graham GJ. Journal of Immunology

 

Ticks produce highly selective chemokine binding proteins with anti-inflammatory activity. Déruaz M, Frauenschuh A, Alessandri AL, Dias JM, Coelho FM, Russo RC, Ferreira BR, Graham GJ, Shaw JP, Wells TN, Teixeira MM, Power CA, Proudfoot AE. The Journal of Experimental Medicine

 

Multiple roles for the C-terminal tail of the chemokine scavenger D6. McCulloch CV, Morrow V, Milasta S, Comerford I, Milligan G, Graham GJ, Isaacs NW, Nibbs RJ. The Journal of Biological Chemistry

 

 

2007

Transcriptional analysis of quiescent and proliferating CD34+ human hemopoietic cells from normal and chronic myeloid leukemia sources. Graham SM, Vass JK, Holyoake TL, Graham GJ. Stem Cells

 

The atypical chemokine receptor D6 suppresses the development of chemically induced skin tumors. Nibbs RJ, Gilchrist DS, King V, Ferra A, Forrow S, Hunter KD, Graham GJ. The Journal of Clinical Investigation

 

The chemokine receptor D6 has opposing effects on allergic inflammation and airway reactivity. Whitehead GS, Wang T, DeGraff LM, Card JW, Lira SA, Graham GJ, Cook DN. American Journal of Respiratory and Critical Care Medicine

 

 

2006

Leukocyte expression of the chemokine scavenger D6. McKimmie CS, Graham GJ. Biochemical Society Transactions

 

A murine specific expansion of the Rhox cluster involved in embryonic stem cell biology is under natural selection. Jackson M, Watt AJ, Gautier P, Gilchrist D, Driehaus J, Graham GJ, Keebler J, Prugnolle F, Awadalla P, Forrester LM. BMC Genomics

 

Chemokine scavenging by D6: a movable feast? Graham GJ, McKimmie CS. Trends in Immunology

 

Cutting edge: the silent chemokine receptor D6 is required for generating T cell responses that mediate experimental autoimmune encephalomyelitis. Liu L, Graham GJ, Damodaran A, Hu T, Lira SA, Sasse M, Canasto-Chibuque C, Cook DN, Ransohoff RM. Journal of Immunology

 

A310 helical turn is essential for the proliferation-inhibiting properties of macrophage inflammatory protein-1 alpha (CCL3). Ottersbach K, McLean J, Isaacs NW, Graham GJ. Blood

 

 

2005

The chemokine receptor D6 limits the inflammatory response in vivo. Jamieson T, Cook DN, Nibbs RJ, Rot A, Nixon C, McLean P, Alcami A, Lira SA, Wiekowski M, Graham GJ. Nature Immunology

2004

Total deletion of in vivo telomere elongation capacity: an ambitious but possibly ultimate cure for all age-related human cancers. de Grey AD, Campbell FC, Dokal I, Fairbairn LJ, Graham GJ, Jahoda CA, Porterg AC. Annal of the New York Academy of Sciences

 

Tachykinins regulate the function of platelets. Graham GJ, Stevens JM, Page NM, Grant AD, Brain SD, Lowry PJ, Gibbins JM. Blood

 

The chemokine receptor D6 constitutively traffics to and from the cell surface to internalize and degrade chemokines. Weber M, Blair E, Simpson CV, O'Hara M, Blackburn PE, Rot A, Graham GJ, Nibbs RJ. Molecular Biology of the Cell

 

Purification and biochemical characterization of the D6 chemokine receptor. Blackburn PE, Simpson CV, Nibbs RJ, O'Hara M, Booth R, Poulos J, Isaacs NW, Graham GJ. The Biochemical Journal

2003

Regulation of glycogen synthase kinase 3 in human platelets: a possible role in platelet function? Barry FA, Graham GJ, Fry MJ, Gibbins JM. FEBS Letters

 

CCL27/PESKY: a novel paradigm for chemokine function. Nibbs RJ, Graham GJ. Expert Opinion on Biological Therapy

2002

Characterization of the binding site on heparan sulfate for macrophage inflammatory protein 1alpha. Stringer SE, Forster MJ, Mulloy B, Bishop CR, Graham GJ, Gallagher JT. Blood

 

The chemokine ESkine/CCL27 displays novel modes of intracrine and paracrine function. Gortz A, Nibbs RJ, McLean P, Jarmin D, Lambie W, Baird JW, Graham GJ. Journal of Immunology

 

Cloning and characterization of Ehox, a novel homeobox gene essential for embryonic stem cell differentiation. Jackson M, Baird JW, Cambray N, Ansell JD, Forrester LM, Graham GJ. The Journal of Biological Chemistry

2001

Macrophage inflammatory protein-1alpha uses a novel receptor for primitive hemopoietic cell inhibition. Ottersbach K, Cook DN, Kuziel WA, Humbles A, Lu B, Gerard C, Proudfoot AE, Graham GJ. Blood

 

In vivo expansion of the endogenous B-cell compartment stimulated by radiation and serial bone marrow transplantation induces B-cell leukaemia in mice. Holyoake TL, Freshney MG, Samuel K, Ansell J, Watson GE, Wright EG, Graham GJ, Pragnell IB. British Journal of Haematology

 

The beta-chemokine receptor D6 is expressed by lymphatic endothelium and a subset of vascular tumors. Nibbs RJ, Kriehuber E, Ponath PD, Parent D, Qin S, Campbell JD, Henderson A, Kerjaschki D, Maurer D, Graham GJ, Rot A. The American Journal of Pathology

 

Aggregation-independent modulation of proteoglycan binding by neutralization of C-terminal acidic residues in the chemokine macrophage inflammatory protein 1alpha. Ottersbach K, Graham GJ. The Biochemical Journal

 

Differentiating embryonal stem cells are a rich source of haemopoietic gene products and suggest erythroid preconditioning of primitive haemopoietic stem cells. Baird JW, Ryan KM, Hayes I, Hampson L, Heyworth CM, Clark A, Wootton M, Ansell JD, Menzel U, Hole N, Graham GJ. The Journal of Biological Chemistry

2000

Aminooxypentane addition to the chemokine macrophage inflammatory protein-1alpha P increases receptor affinities and HIV inhibition. Townson JR, Graham GJ, Landau NR, Rasala B, Nibbs RJ. The Journal of Biological Chemistry

 

CFU-A assay for measurement of the antiproliferative effects of chemokines on murine early hemopoietic progenitors. Graham GJ, Freshney MG. Methods in Molecular Biology

 

Cutting edge: identification of the orphan receptor G-protein-coupled receptor 2 as CCR10, a specific receptor for the chemokine ESkine. Jarmin DI, Rits M, Bota D, Gerard NP, Graham GJ, Clark-Lewis I, Gerard C. Journal of Immunology

 

C-C chemokine receptor 3 antagonism by the beta-chemokine macrophage inflammatory protein 4, a property strongly enhanced by an amino-terminal alanine-methionine swap. Nibbs RJ, Salcedo TW, Campbell JD, Yao XT, Li Y, Nardelli B, Olsen HS, Morris TS, Proudfoot AE, Patel VP, Graham GJ. Journal of Immunology