Pan-viral protection against arboviruses by activating skin macrophages at the inoculation site. Bryden SR, Pingen M, Lefteri DA, Miltenburg J, Delang L, Jacobs S, Abdelnabi R, Neyts J, Pondeville E, Major J, Müller M, Khalid H, Tuplin A, Varjak M, Merits A, Edgar J, Graham GJ, Shams K, McKimmie CS. Science Translational Medicine.

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Human umbilical cord perivascular cells improve human pancreatic islet transplant function by increasing vascularization.

Forbes S, Bond AR, Thirlwell KL, Burgoyne P, Samuel K, Noble J, Borthwick G, Colligan D, McGowan NWA, Lewis PS, Fraser AR, Mountford JC, Carter RN, Morton NM, Turner ML, Graham GJ, Campbell JDM. Science Translational Medicine.

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Sustained exposure to systemic endotoxin triggers chemokine induction in the brain followed by a rapid influx of leukocytes

Carolyn A. Thomson, Alison McColl, Gerard J. Graham Jonathan Cavanagh Journal of Neuroinflammation

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Mild Inflammation in Healthy Males Induces Fatigue Mediated by Changes in Effective Connectivity Within the Insula

Kristian Stefanov, John McLean, Alison McColl, Neil Basu, Jonathan Cavanagh, Rajeev Krishnadas

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Chemokine receptors coordinately regulate macrophage dynamics and mammary gland development.

Wilson GJ, Fukuoka A, Love SR, Kim J, Pingen M, Hayes AJ, Graham GJ. Development 

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Pancreas-derived mesenchymal stromal cells share immune response-modulating and angiogenic potential with bone marrow mesenchymal stromal cells and can be grown to therapeutic scale under Good Manufacturing Practice conditions.

Thirlwell KL, Colligan D, Mountford JC, Samuel K, Bailey L, Cuesta-Gomez N, Hewit KD, Kelly CJ, West CC, McGowan NWA, Casey JJ, Graham GJ, Turner ML, Forbes S, Campbell JDM. Cytotherapy. 2020 Dec;22(12):762-771. doi: 10.1016/j.jcyt.2020.07.010. Epub 2020 Aug 20. PMID: 32828673.

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Role of placental inflammatory mediators and growth factors in patients with rheumatic diseases with a focus on systemic sclerosis.

Motta F, Codullo V, Ramoni V, Cesari S, Ferrario G, Fiandrino G, Beneventi F, Rampello S, Johnsson H, Montecucco C, Graham GJ. Rheumatology (Oxford). 2021 Jul 1;60(7):3307-3316. doi: 10.1093/rheumatology/keaa782. PMID: 33313931; PMCID: PMC8516508.
 

Role of inflammatory chemokines in hypertension.

Mikolajczyk TP, Szczepaniak P, Vidler F, Maffia P, Graham GJ, Guzik TJ. Pharmacol Ther. 2021 Jul;223:107799. doi: 10.1016/j.pharmthera.2020.107799. Epub 2020 Dec 24. PMID: 33359600.

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Chemokines and their receptors: predictors of the therapeutic potential of mesenchymal stromal cells.

Cuesta-Gomez N, Graham GJ, Campbell JDM. J Transl Med. 2021 Apr 17;19(1):156. doi: 10.1186/s12967-021-02822-5. PMID: 33865426; PMCID: PMC8052819.

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Diverse myeloid cells are recruited to the developing and inflamed mammary gland.

Wilson GJ, Fukuoka A, Vidler F, Graham GJ. Immunology. 2022 Feb;165(2):206-218. doi: 10.1111/imm.13430. Epub 2021 Nov 30. PMID: 34775606; PMCID: PMC10357480.

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CCR7+ dendritic cells sorted by binding of CCL19 show enhanced Ag-presenting capacity and antitumor potencyBurgoyne P, Hayes AJ, Cooper RS, Le Brocq ML, Hansell CA, Campbell JD, Graham GJ. . J Leukoc Biol. 2022 Jun;111(6):1243-1251. doi: 10.1002/JLB.5AB0720-446RR. Epub 2021 Nov 15. PMID: 34780080.

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The atypical chemokine receptor-2 fine-tunes the immune response in herpes stromal keratitis.​

Yu T, Schuette F, Christofi M, Forrester JV, Graham GJ, Kuffova L. Front Immunol. 2022 Nov 28;13:1054260. doi: 10.3389/fimmu.2022.1054260. PMID: 36518752; PMCID: PMC9742518.

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Inflammatory Chemokine Receptors Support Inflammatory Macrophage and Dendritic Cell Maturation.

Bartolini R, Medina-Ruiz L, Hayes AJ, Kelly CJ, Halawa HA, Graham GJ. Immunohorizons. 2022 Nov 1;6(11):743-759. doi: 10.4049/immunohorizons.2200069. PMID: 36426967.

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Analysis of combinatorial chemokine receptor expression dynamics using multi-receptor reporter mice.

Medina-Ruiz L, Bartolini R, Wilson GJ, Dyer DP, Vidler F, Hughes CE, Schuette F, Love S, Pingen M, Hayes AJ, Fu J, Stewart AF, Graham GJ. Elife. 2022 Jun 14;11:e72418. doi: 10.7554/eLife.72418. PMID: 35699420; PMCID: PMC9236609.

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Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate widespread immune cell recruitment independent of chemokine receptors.

​Gray AL, Karlsson R, Roberts ARE, Ridley AJL, Pun N, Khan B, Lawless C, Luís R, Szpakowska M, Chevigné A, Hughes CE, Medina-Ruiz L, Birchenough HL, Mulholland IZ, Salanga CL, Yates EA, Turnbull JE, Handel TM, Graham GJ, Jowitt TA, Schiessl I, Richter RP, Miller RL, Dyer DP. Cell Rep. 2023 Jan 31;42(1):111930. doi: 10.1016/j.celrep.2022.111930. Epub 2023 Jan 5. PMID: 36640356; PMCID: PMC11064100.

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IL-6 and TGF-β-Secreting Adoptively-Transferred Murine Mesenchymal Stromal Cells Accelerate Healing of Psoriasis-like Skin Inflammation and Upregulate IL-17A and TGF-β.

Cuesta-Gomez N, Medina-Ruiz L, Graham GJ, Campbell JDM. Int J Mol Sci. 2023 Jun 14;24(12):10132. doi: 10.3390/ijms241210132. PMID: 37373278; PMCID: PMC10298958.

 

Disruption of placental ACKR3 impairs growth and hematopoietic development of offspring.

​Fukuoka A, Wilson GJ, Pitmon E, Koumbas Foley L, Johnsson H, Pingen M, Graham GJ. Development. 2024 Feb 15;151(4):dev202333. doi: 10.1242/dev.202333. Epub 2024 Feb 23. PMID: 38300826; PMCID: PMC10911115.​​​

 

CCR1 and CCR2 Coexpression on Monocytes Is Nonredundant and Delineates a Distinct Monocyte Subpopulation.

​Medina-Ruiz L, Bartolini R, Mathie H, Halawa HA, Cunningham M, Graham GJ. J Immunol. 2024 Jul 15;213(2):214-225. doi: 10.4049/jimmunol.2400007. Erratum in: J Immunol. 2024 Nov 15;213(10):1569. doi: 10.4049/jimmunol.2400470. PMID: 38829123; PMCID: PMC11215633.​​​

 

Enhanced CCR2 expression by ACKR2-deficient NK cells increases tumoricidal cell therapy efficacy.

Hayes AJ, Pingen M, Wilson G, Hansell C, Love S, Burgoyne P, McElroy D, Bartolini R, Vidler F, Schuette F, Gamble A, Campbell J, Galatis D, Campbell JDM, Graham GJ. J Leukoc Biol. 2024 Nov 27;116(6):1544-1553. doi: 10.1093/jleuko/qiae162. PMID: 39052923.​​​

 

Inflammatory chemokine receptors CCR1, CCR2, CCR3 and CCR5 are essential for an optimal T cell response to influenza.

Pingen M, Hughes CE, Medina-Ruiz L, Mathie H, Barrie JA, Hansell CA, Bartolini R, MacLeod MK, Graham GJ. I Mucosal Immunol. 2025 Aug;18(4):951-957. doi: 10.1016/j.mucimm.2025.05.005. Epub 2025 May 23. PMID: 40414601.