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2015

An atypical addition to the chemokine receptor nomenclature: IUPHAR Review 15. Bachelerie F, Graham GJ, Locati M, Mantovani A, Murphy PM, Nibbs R, Rot A, Sozzani S, Thelen M. British Journal of Pharmacology.

 

D6/ACKR2.  Graham GJ.  Frontiers in Immunology.

 

The atypical chemokine receptor ACKR2 suppresses Th17 responses to protein autoantigens. Hansell CA, MacLellan LM, Oldham RS, Doonan J, Chapple KJ, Anderson EJ, Linington C, McInnes IB, Nibbs RJ, Goodyear CS. Immunology and Cell Biology.

2014

The chemokine receptors ACKR2 and CCR2 reciprocally regulate lymphatic vessel density. Lee KM, Danuser R, Stein JV, Graham D, Nibbs RJ, Graham GJ. EMBO Journal

 

IL-33 promotes ST2-dependent lung fibrosis by the induction of alternatively activated macrophages and innate lymphoid cells in mice. Li D, Guabiraba R, Besnard AG, Komai-Koma M, Jabir MS, Zhang L, Graham GJ, Kurowska-Stolarska M, Liew FY, McSharry C, Xu D. Journal of Allergy and Clinical Immunology

 

Flow cytometry applications for the analysis of chemokine receptor expression and function. Anselmo A, Mazzon C, Borroni EM, Bonecchi R, Graham GJ, Locati M. Cyometry A

 

Chemokines as novel and versatile reagents for flow cytometry and cell sorting. Le Brocq ML, Fraser AR, Cotton G, Woznica K, McCulloch CV, Hewit KD, McKimmie CS, Nibbs RJ, Campbell JD, Graham GJ. Journal of Immunology

 

Characterization of conventional and atypical receptors for the chemokine CCL2 on mouse leukocytes. Ford LB, Cerovic V, Milling SW, Graham GJ, Hansell CA, Nibbs RJ. Journal of Immunology

2013

Increased number and altered phenotype of lymphatic vessels in peripheral lung compartments of patients with COPD. Mori M, Andersson CK, Graham GJ, Löfdahl CG, Erjefält JS. Respiratory Research

 

Cell-autonomous regulation of neutrophil migration by the d6 chemokine decoy receptor. Rot A, McKimmie C, Burt CL, Pallas KJ, Jamieson T, Pruenster M, Horuk R, Nibbs RJ, Graham GJ. Journal of Immunology

 

An analysis of the function and expression of D6 on lymphatic endothelial cells. McKimmie CS, Singh MD, Hewit K, Lopez-Franco O, Le Brocq M, Rose-John S, Lee KM, Baker AH, Wheat   R, Blackbourn DJ, Nibbs RJ, Graham GJ. Blood

 

Suppression, subversion and escape: the role of regulatory T cells in cancer progression. Oleinika K, Nibbs RJ, Graham GJ, Fraser AR. Clinical and Experimental Immunology

 

CCX-CKR deficiency alters thymic stroma impairing thymocyte development and promoting autoimmunity. Bunting MD, Comerford I, Seach N, Hammett MV, Asquith DL, Körner H, Boyd RL, Nibbs RJ, McColl SR. Blood

 

Using fluorescent chemokine uptake to detect chemokine receptors by fluorescent activated cell sorting. Ford LB, Hansell CA, Nibbs RJ. Methods in Molecular Biology

 

Bcl-3 deficiency protects against dextran-sodium sulphate-induced colitis in the mouse. O'Carroll C, Moloney G, Hurley G, Melgar S, Brint E, Nally K, Nibbs RJ, Shanahan F, Carmody RJ. Clinical and Experimental Immunology

 

Regulation of the immune and inflammatory responses by the 'atypical' chemokine receptor D6. Graham GJ, Locati M. Journal of Pathology

 

D6: the 'crowd controller' at the immune gateway. Lee KM, Nibbs RJ, Graham GJ. Trends in Immunology

 

Microarray analyses demonstrate the involvement of Type I Interferons in psoriasiform pathology development in D6 deficient mice. Baldwin HM, Pallas K, King V, Jamieson T, McKimmie CS, Nibbs RJ, Carballido JM, Jaritz M, Rot A, Graham GJ. The Journal of Biological Chemistry

 

International Union of Pharmacology. LXXXIX. Update on the Extended Family of Chemokine Receptors and Introducing a New Nomenclature for Atypical Chemokine Receptors. Bachelerie F, Ben-Baruch A, Burkhardt AM, Combadiere C, Farber JM, Graham GJ, Horuk R, Sparre-Ulrich AH, Locati M, Luster AD, Mantovani A, Matsushima K, Murphy PM, Nibbs R, Nomiyama H, Power CA, Proudfoot AE, Rosenkilde MM, Rot A, Sozzani S, Thelen M, Yoshie O, Zlotnik A. Pharmacological Reviews

 

Immune Regulation by Atypical Chemokine Receptors. Nibbs RJ and Graham GJ. Nature Reviews Immunology

2012

The biochemistry and biology of the atypical chemokine receptors. Graham GJ, Locati M, Mantovani A, Rot A, Thelen M. Immunology Letters

 

Elevated expression of the chemokine-scavenging receptor D6 is associated with impaired lesion development in psoriasis. Singh MD, King V, Baldwin H, Burden D, Thorrat A, Holmes S, McInnes IB, Nicoll R, Shams K, Pallas K, Jamieson T, Lee KM, Carballido JM, Rot A, Graham GJ. American Journal of Pathology

 

Acute inflammatory response to cobalt chromium orthopaedic wear debris in a rodent air-pouch model. Akbar M, Fraser AR, Graham GJ, Brewer JM, Grant MH. Journal of the Royal Society Interface

2011

D6 facilitates cellular migration and fluid flow to lymph nodes by suppressing lymphatic congestion. Lee KM, McKimmie CS, Gilchrist DS, Pallas KJ, Nibbs RJ, Garside P, McDonald V, Jenkins C, Ransohoff R, Liu L, Milling S, Cerovic V, Graham GJ. Blood

 

IL-33 induces skin inflammation with mast cell and neutrophil activation. Hueber AJ, Alves-Filho JC, Asquith DL, Michels C, Millar NL, Reilly JH, Graham GJ, Liew FY, Miller AM, McInnes IB. European Journal of Immunology

 

An investigation of the inflammatory cytokine and chemokine network in systemic sclerosis. Codullo V, Baldwin HM, Singh MD, Fraser AR, Wilson C, Gilmour A, Hueber AJ, Bonino C, McInnes IB, Montecucco C, Graham GJ. Annals of the Rheumatic Diseases

2010

Astrocytes modulate the chemokine network in a pathogen-specific manner. McKimmie CS, Graham GJ. Biochemical and Biophysical Research Communications

 

IL-7 induces rapid clathrin-mediated internalization and JAK3-dependent degradation of IL-7Ralpha in T cells. Henriques CM, Rino J, Nibbs RJ, Graham GJ, Barata JT. Blood

 

Chemokine scavenger D6 is expressed by trophoblasts and aids the survival of mouse embryos transferred into allogeneic recipients. Madigan J, Freeman DJ, Menzies F, Forrow S, Nelson SM, Young A, Sharkey A, Moffett A, Graham GJ, Greer IA, Rot A, Nibbs RJ. Journal of Immunology

Spread of psoriasiform inflammation to remote tissues is restricted by the atypical chemokine receptor ACKR2. Shams K, Wilson GJ, Singh M, van den Bogaard EH, Le Brocq ML, Holmes S, Schalwijk J, Burden AD, McKimmie CS, Graham GJ. The Journal of Investigative Dermatology.

CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cells. Sinclair A, Park L, Shah M, Drotar M, Calaminus S, Hopcroft LE, Kinstrie R, Guitart AV, Dunn K, Abraham SA, Sansom O, Michie AM, Machesky L, Kranc KR, Graham GJ, Pellicano F, Holyoake TL. Blood.

Host inflammatory response to mosquito bites enhances the severity of arbovirus infection. Pingen M, Bryden SR, Pondeville E, Schnettler E, Kohl A, Merits A, Fazakerley JK, Graham GJ, McKimmie CS. Immunity.

TLR7-mediated skin inflammation remotely triggers chemokine expression and leukocyte accumulation in the brainMcColl A, Thomson CA, Nerurkar L, Graham GJ, Cavanagh J. Journal of Neuroinflammation.

ACRK4 on stromal cells scavenges CCL19 to enable CCR7-dependent trafficking of antigen-presenting cells from inflamed skin to lymph nodes. Bryce SA, Wilson RAM, Tiplady EM, Asquith DL, Bromley SK, Luster AD, Graham GJ, Nibbs R. Journal of Immunology.

Atypical chemokine receptors and their roles in the resolution of the inflammatory response. Bonecchi R, Graham GJ. Frontiers in Immunology.

The ability to cross the blood-cerebrospinal fluid barrier is a generic property of acute lymphoblastic leukemia blasts. Williams MT, Yousafzai YM, Elder A, Rehe K, Bomken S, Frishman-Levy L, Taylor S, Sinclair P, Dormon K, Masic D, Perry T, Weston VJ, Kearns P, Blair H, Russell LJ, Heidenreich O, Irving JA, Izraeli S, Vormoor J, Graham GJ, Halsey C. Blood.

2016

Atypical chemokine receptor ACKR2 controls branching morphogenesis in the developing mammary glandWilson GJ, Hewit KD, Pallas KJ, Cairney CJ, Lee KM, Hansell CA, Stein T, Graham GJ. Development.

2017